MT-1 · α-MSH Analog · MC1R Agonist · 10mg/vial · Research Grade
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NOT FOR HUMAN CONSUMPTION. Sold for Research, Novelty, and Collection Purposes only. Must be 21+.
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Compound Overview
Classification
Melanotan 1 (MT-1, afamelanotide) is a synthetic analog of alpha-melanocyte-stimulating hormone (α-MSH), a 13-amino acid peptide derived from proopiomelanocortin (POMC). A selective MC1R agonist, MT-1 stimulates melanogenesis in melanocytes without the broader melanocortin receptor activity seen in MT-2. Extensively studied for photoprotection, pigmentation research, and inflammatory modulation.
Mechanisms of Action
Selectively activates melanocortin 1 receptors on melanocytes, triggering eumelanin production — the protective dark pigment that absorbs UV radiation.
Stimulates tyrosinase enzyme activity and melanin synthesis, increasing baseline pigmentation in skin research models.
MC1R activation on immune cells suppresses NF-κB signaling and reduces pro-inflammatory cytokine production, independent of pigmentation effects.
Increased eumelanin confers UV absorption capacity; studied as a mechanism for reducing UV-induced DNA damage in photodermatology research.
Research Findings
Photoprotection
Demonstrated reduction in UV-induced phototoxicity in erythropoietic protoporphyria (EPP) clinical research
Melanogenesis
Dose-dependent increases in skin pigmentation observed across multiple human and animal research studies
Anti-inflammatory
MC1R-mediated suppression of inflammatory pathways studied in skin and systemic inflammation models
Research Areas
Photoprotection and UV damage prevention
Pigmentation and melanogenesis biology
Erythropoietic protoporphyria (EPP) models
Skin cancer and photodermatology research
Inflammatory skin disease studies
MC1R signaling pathway investigation
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FDA Disclosure
The statements made regarding our products have not been evaluated by the Food and Drug Administration (FDA). These products are not intended to diagnose, treat, cure, or prevent any disease. All information is for educational purposes only and is not a substitute for medical advice. Do not use if pregnant, nursing, or under 21.
MgBotanic is not liable for any adverse effects or misuse of its products.
Product Description
Product is NOT FOR HUMAN CONSUMPTION. Sold strictly for Research, Novelty, and Collection Purposes only. Not intended for human or animal consumption.
Age Restriction — 21+
This product is intended for adults 21 years and older. By purchasing, you confirm you are at least 21 years of age.
No Liability
By purchasing this product, you agree that the seller is not responsible for any adverse effects or consequences resulting from the use or misuse of this product. All products are sold for legal use only.